Hello, thanks for your question.
The below recipe is a fabulous whoopie pie recipe that has been tested in our kitchens. We are confident if you substitute the red velvet cake mix for the Devil's food mix, and omit the red food coloring, you will achieve the same desired result. So yes, use the other ingredients called for along with the cake mix for the cookie cake part (the pudding mix, eggs, water and oil)
You can substitute whatever type of filling you would like, whether it be a marshmallow buttercream or prepared cream cheese icing.
Answered 11/28/2012 by mgoetz